7 years since I built a PC for MC.  Based on comments here, I've put together this parts list for you to mock or love!  I'm open to changing all of this, so feel free to pick it apart!!!

- CPU:  Intel Core i7-7820x    $560

- MB:  Asus Rog Strix x299-E Gaming Motherboard    $320

- RAM:  Ballistix Sport 64GB Kit 16x4 sticks. DDR4 2400    $670

- PNY Quadro P2000-PB Video Card   $400

- Windows 10 64bit Pro    $150

- SSD, Case, Media Drives from current PC.

Thoughts?  Comments?  Seething Hatred?  Let me know!!!

Most of my picks stem from this thread:  http://community.avid.com/forums/t/180415.aspx?PageIndex=2  So, that's why it is what it is.

Will you be using the stock CPU Intel cooler?

I would go with a GeForce card over the Quadro. And I'd consider the 8th gen i7 8700K.

I used the ASUS X299 with the 7820 - works great!

One suggestion would be a high speed M.2 SSD for the boot drive.

Given the 8 cores I suggest liquid cooling as my massive air cooler still cant cope with anything but a minor overclock.

I also fitted a quadro M2000 - no issues

Parts of MC are still not optimised to use all the cores fully so dont be surprised if its not as fast as you think it should be.  But mostly its very good.

I'm torn because the Quadros have always been "more" supported.  I guess now, the GeForce cards are really equally supported. Stability is my main concern.

For the CPU, I like the suggestion of the 8700K - it seems faster and is considerably cheaper. I will be using the stock cooler. I don't want to mess with water cooling.

I have an SSD that I'll use already. 

I guess now I just need to decide if a 1070 video card would be the better choice... hmmm.

P2000 works very well with MC.

If you want the PC for playing games go for the 1070.

For faster editing a kind of OC of the CPU is recommended.

I run mine for 7 years from 3.4 to 4.4 with a better 12cm fan.

The difference in rendering is more than obvious to the point that after so many years I can edit 4K fine

even linked on AMA (which the P2000 helps also a lot).

However if you don't know to do it or you are not sure how, stick to the default setup.

Atomike:

I'm torn because the Quadros have always been "more" supported.  I guess now, the GeForce cards are really equally supported. Stability is my main concern.

For the CPU, I like the suggestion of the 8700K - it seems faster and is considerably cheaper. I will be using the stock cooler. I don't want to mess with water cooling.

I have an SSD that I'll use already. 

I guess now I just need to decide if a 1070 video card would be the better choice... hmmm.

The 8700 should also be a little faster for apps that aren't super well optimized for multithreading, MC fits into that category.

You might want to jump up to the 1070 Ti or the 1080. As for the Quadro, I'd suggest watching this: https://www.youtube.com/watch?v=LC_sx6A5Wko

That was a fairly eye-opening video.

Since I also do 3D animation with Blender, I'm now leaning toward the 1070 Ti card for graphics.

Very glad I started this thread.

Mike, I would also *consider* using an M.2 NVME PCIe 3 x4 SSD for a boot and programs drive. Personally, I don't care much about boot times, but the argument could be made that if you're making a new system you might as well use the latest in drive performance.

Also pay attention to the PCIe slot configuration of the z370 motherboard and its number of total PCIe lanes.

If you are planning on running two graphics cards, then the z370 will not offer enough PCIe slots to run both at x16. So in that case, you should consider going with x299. But the practical advantage of x16 over x8 with PCIe 3.0 is considered to be negligable with today's graphics cards. 

I would go for cores - 7820 = 8 core  (vs 6 core)  But it does need decent cooling.

Older design with two more but slower cores vs newer design with two less but faster cores. There are good arguments to go either way. From the tests I've seen, unless the program is very well optimized to take advantage of multiple cores, the 8700 will be faster.

IMHO, for MC faster cores are better than more cores. Of course, faster and more would be better still.